Description
Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with Familial Amyloidoticpolyneuropathy (FAP) which is a fatal disease, characterized by amyloid depositions found in visceral organs including the heart, liver and kidneys. TTR V30M is a common variant associated with FAP found in Sweden, Portugal and Japan.
Amount
1mg
Format
Lyophilized
Molecular Weight
13792 Da
Sequence
GPTGTGESKCPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSES GELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRY TIAALLSPYSYSTTAVVTNPKE
Purity
95% by Chromatography and SDS-PAGE
Counter Ion
Ammonium Carbonate
Solubility
The lyophilized protein is readily soluble in PBS pH 7.4.
Storage
Store at -20°C upon arrival.
Source
Protein expressed in Escherichia coli.
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