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Polyclonal Antiserum to Human C9 Protein
品牌:Quidel
貨號:A310
規格:A310
貨期:Quidel

品牌:Quidel 貨號:A310 品名:Polyclonal Antiserum to Human C9 Protein 規格:2.00 mL

商品詳情 參考文獻 相關資料

產品介紹

品名

Polyclonal Antiserum to Human C9 Protein

貨號

A310

規格

2.0 mL 

標本類型

Unformed stool

防腐劑

≤ 0.1% Sodium Azide

物種交叉反應

Baboon, Horse, Rabbit, Hamster, Rhesus macaque

儲存

2°C to 8°C  (≤ 30 days)

For long-term storage (> 30 days), aliquot and store at ≤ –20°C. Avoid repeated freeze-thaw.

使用說明

For Research Use Only. Not for use in diagnostic procedures

產品描述

Highly purified human C9 was isolated from normal serum and used to immunize goats. The anti-human C9 polyclonal antisera was tested against normal human plasma by double immunodiffusion, one-dimensional immunoelectrophoresis, quantitative radial immunodiffusion, and quantitative rocket immunoelectrophoresis. The antiserum was determined to be monospecific for C9 at varying concentrations

背景

C9 is a glycoprotein which is present in normal human serum/plasma at approximately 55 μg/mL. Primarily synthesized in the liver, C9 is a single-chain protein with a molecular weight of approximately 71 kD. This complement protein is amphiphilic in nature, and can be fragmented by human α-thrombin to produce C9a and C9b. The hydrophilic domain of the C9 complex becomes the C9a fragment and has an approximate molecular weight of 34 kD. The hydrophobic end becomes C9b fragment, which has an approximate molecular weight of 37 kD.

應用

Applications of the C9 polyclonal antisera have been evaluated by various research facilities, and include Western Blot, 1 Immunodepletion, 2 Immunofluorescence, 3,4,5 IHC, 6,7 and ELISA. 8

參考文獻

Marks, R., Hindmarsh, E. Complement activation occurs on subendothelial extracelluslar matrix in vitro and is initiated by retraction or removal of overlying endothelial cells, J Immunol 160:6128-6136, 1998.

Barbashov, S., Wang C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997
















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