Raised against a 19 amino acid peptide from near the carboxy terminus of human FAM59A.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Affinity chromatography purified via peptide column
Formulation:
Supplied in PBS containing 0.02% sodium azide.
Storage:
Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
Function:
Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation (By similarity).
Sequence Similarities:
Belongs to the GAREM family.
Post-Translational Modification:
On EGF stimulation, phosphorylated on Tyr-105 and Tyr-453.
Database Links:
Entrez Gene: 64762?Human
Entrez Gene: 381126?Mouse
SwissProt: Q9H706?Human
SwissProt: Q3UFT3?Mouse
Unigene: 444314?Human
Unigene: 312276?Mouse
Synonyms:
FA59A_HUMAN Antibody
FAM59A Antibody
Family with sequence similarity 59, member A Antibody
GAREM Antibody
Gm944 Antibody
Protein FAM59A Antibody
Information:
Target information shown above is from the UniProt Consortium.