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Anthrax Toxins (Anthrax Protective Antigen & Derivitives) Protective antigen (PA) is the receptor binding component of anthrax toxin. The original 83 kDa protein is cleaved by cellular furin-like proteases to form an activated 63 kDa monomer, PA63. In this form, PA63 binds to other PA63 molecules forming a ring-shaped heptamer. PA63 also has s specific for the enzymes LF and EF adjacent to the pore formed on the cell surface for translocation. PA should be used in approximately seven-fold excess along with either EF or LF to intoxicate cells. List Labs provides PA in three different sizes, Product #171 is the uncleaved 83 kDa protein, Product #s 174 and 175 are PA63, which has been activated and purified, and PA63 conjugated to FITC, respectively. Additionally we provide the approximately 20 kDA fragment cleaved from PA, PA20, Product #177 Anthrax PA 63 - FITC Conjugate Anthrax PA 63 - FITC Conjugate #175 Anthrax Protective Antigen (PA),
Recombinant from B. anthracis Anthrax Protective Antigen (PA), Recombinant from B. anthracis #171E Anthrax Protective Antigen Fragment (PA 20)
from B. anthracis Anthrax Protective Antigen Fragment (PA 20) from B. anthracis #177A, #177B Anthrax Protective Antigen,
Activated (PA 63) from B. anthracis Anthrax Protective Antigen, Activated (PA 63) from B. anthracis #174 QD Anthrax Protective Antigen (PA),
Recombinant from B. anthracis QD Anthrax Protective Antigen (PA), Recombinant from B. anthracis QD Anthrax Protective Antigen (PA), Recombinant from B. anthracis